Rabbit Anti-Integrin Alpha V + Beta 6 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Integrin Alpha V + Beta 6
IR:Immunogen Range:
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:3685
Swiss Prot:P06756
Source:KLH conjugated synthetic peptide derived from human Integrin Alpha V + Beta 6:
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. Integrin alpha-v beta-6 is upregulated in cancers and during tissue remodelling but is absent from resting adult tissues. Integrin alpha-v beta-6 promotes invasion and correlates with poor survival and therefore makes a promising therapeutic target.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1μg/Test)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: Integrin Alpha V + B;Integrin alpha 5 bet;CD51;ntegrin alpha-V ligh;ntegrin, alpha V;ITGB6;Integrin;ITAV_HUMAN;
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