Rabbit Anti-RAB8A Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:RAB8A
IR:Immunogen Range:101-207/207
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:4218
Swiss Prot:P61006
Source:KLH conjugated synthetic peptide derived from human RAB8A:101-207/207
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Cow
Sheep
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： RAB8A;MEL;Mel transforming onc;Oncogene c mel;ncogene c-mel;RAB8;RAB8A ;RAB8A_HUMAN;
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