Rabbit Anti-Staufen Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Staufen
IR:Immunogen Range:421-520/577
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:6780
Swiss Prot:O95793
Source:KLH conjugated synthetic peptide derived from human Staufen/STAU1:421-520/577
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:STAU1 (staufen, RNA binding protein, homolog 1) is a 577 amino acid protein that contains three double-stranded RNA-binding domains and is a mammalian homolog of Staufen, a Drosophila protein that is involved in mRNA transport during oogenesis and zygotic development. Localized to the rough endoplasmic reticulum (RER) and expressed in a variety of tissues, including heart, brain, liver, lung, pancreas, kidney and placenta, STAU1 binds to both Tubulin and double-stranded RNA and is thought to play an important role in mRNA transport from the microtubule network to the RER. Additionally, STAU1 may be involved in cross-linking cytoskeletal components with RNA, an event that is important for proper mRNA positioning during translation. Alternative splicing of the STAU1 gene yields two STAU1 isoforms, designated short and long.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:50-200)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Cow
Horse
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： Staufen;RNA-binding protein ;Double-stranded ;FLJ25010;MGC124588;STAU;STAU1;STAU1_HUMAN;
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