Rabbit Anti-Nm23-H2/NME2 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Nm23-H2/NME2
IR:Immunogen Range:21-100/152
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:4831
Swiss Prot:P22392
Source:KLH conjugated synthetic peptide derived from human Nm23:21-100/152
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:NM23 is a heterodimeric protein functioning as a nucleoside diphosphate (NDP) kinase. NME1 and NME2 comprise the 152 amino acid A and B polypeptide chains of the NM23 enzyme, respectively. NME2 is identical to the beta subunit of human erythrocyte NDP kinase. NDP kinases are involved in the synthesis of nucleoside triphosphates, and NM23 may act in the regulation of signal transduction by complexing with G proteins, causing activation/inactivation of developmental pathways. NEM2 has been identified as a putative tumor suppressor. High expression of mouse NME2 is detected in heart, liver, and kidney, with moderate expression in skeletal muscle, and negligible expression in other mouse tissues examined.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: Nm23-H2/NME2;别 名nucleoside dIP;NDKB;NDP kinase B;NDPKB;NM23 H2;NM23B;MGC111212;
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