Rabbit Anti-gamma tubulin Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:gamma tubulin
IR:Immunogen Range:351-451/451
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:7283
Swiss Prot:P23258
Source:KLH conjugated synthetic peptide derived from human Tubulin gamma-1 chain:351-451/451
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Centrosome Marker
Gamma tubulin, a member of the tubulin superfamily, is a ubiquitous and highly conserved protein within the microtubule organizing centre (MTOC). Gamma tubulin is not a component of microtubules, rather it functions as the microtubule nucleator at the MOTC, is responsible for binding microtubule minus ends and mediating the link between microtubles and the centrosome. By binding to the beta tubulin subunit of the tubulin molecule, it establishes the polarity of a microtubule leaving the alpha tubulin subunit exposed at the positive end.
The abundance of Gamma tubulin is less than 1% of the level of either alpha or beta tubulin. It shares approximately 28-32% identity with alpha tubulin from various organisms and 32-36% identity with beta tubulins. The detection, localization and characterization of proteins involved in microtubule function is fundamental to the understanding of mitosis, meiosis and the microtubule cytoskeleton.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Rabbit
Guinea Pig
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： gamma tubulin;Centrosome Marker;Gamma 1 tubulin;gamma-tubulin;MGC131994;GCP1;TUBG2;TBG2_HUMAN;
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