Rabbit Anti-MSRB2 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:MSRB2
IR:Immunogen Range:31-130/182
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:22921
Swiss Prot:Q9Y3D2
Source:KLH conjugated synthetic peptide derived from human MSRB2:31-130/182
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Methionine is one of the most readily oxidized essential amino acids and an intermediate in the biosynthesis of cysteine, carnitine, taurine, lecithin, phosphatidylcholine and other phospholipids. In its oxidative state, Methionine is regulated in vivo by methionine sulfoxide reductases (Msr). MsrB2 is a 182 amino acid mitochondrial protein that is ubiquitously expressed. Belonging to the MsrB Met sulfoxide reductase family, MsrB2 acts as a catalyst for the reduction of free and protein-bound methionine sulfoxide to methionine. Upon oxidative stress, MsrB2 is suggested to play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance. MsrB2 utilizes zinc ions, one per subunit, as cofactors.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Horse
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： MSRB2;CBS1;CGI 131;Methionine sulfoxide;MGC26104;mitochondrial;MSRB;MSRB2_HUMAN;
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