Rabbit Anti-CYP1A1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:CYP1A1
IR:Immunogen Range:361-460/512
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:57491
Swiss Prot:A9YTQ3
Source:KLH conjugated synthetic peptide derived from human CYP1A1:361-460/512
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The Cytochrome P450 (P450) superfamily of enzymes is one of three enzyme systems which metabolize the fatty acid arachadonic acid (AA) to regulators of vascular tone. P450 enzymes are monooxygenase enzymes which require several cofactors such as nicotinamide adenine dinucleotide phosphate (NADPH) and P450 reductase. There are over 200 known genes which encode P450s. Epoxygenases are those P450s which metabolize AA to epoxyeicosatrienoic acid (EETs) and omega hydroxylases are those P450s which produce 19- and 20-hydroxyeicosatetraenoic acids (19- and 20-HETE). As well as fatty acid metabolism, P450s also metabolize many drugs and toxins. Cytochrome P450 3A4 is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids and rifampicin.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Pig
.
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： CYP1A1;Cytochrome p450 1A1;AHH;AHRR;CP11;CYP1;P450DX;CYPIA1;
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