Rabbit Anti-FOXL2 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:FOXL2
IR:Immunogen Range:71-170/376
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:668
Swiss Prot:P58012
Source:KLH conjugated synthetic peptide derived from human FOXL2:71-170/376
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis throught transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Rabbit
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: FOXL2;blepharophimosis;forkhead box L2;Forkhead box protein;FOX L2;FOXL2_HUMAN;PINTO;PFRK;
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