Rabbit Anti-MEK6 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:MEK6
IR:Immunogen Range:251-334/334
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:5608
Swiss Prot:P52564
Source:KLH conjugated synthetic peptide derived from human MEK6:251-334/334
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Mitogen activated protein kinase kinase 6 (MEK6 or MKK6) belongs to the serine/threonine protein kinase family and the MAPK kinase subfamily (MAP2K, MKK or MEKs). MEK6, closely related to MEK3, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in MAP kinase p38, thus activating it, in response to inflammatory cytokines and environmental stress.
As an essential component of p38 MAP kinase mediated signal transduction pathway, this protein is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Rabbit
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： MEK6;MAP kinase kinase 6;MAPKK6;MAP2K6;Mitogen Activated Pr;MKK 6;SAPKK3;MP2K6_HUMAN;
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