Rabbit Anti-FPRL1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:FPRL1
IR:Immunogen Range:51-150/351
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:2358
Swiss Prot:P25090
Source:KLH conjugated synthetic peptide derived from human FPRL1:51-150/351
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:FPRL1 is a low affinity receptor to N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). FPRL1 has been reported in phagocytes, monocytes, neutrophils, differentiated myeloid cells from bone marrow, granulocyte HL-60 cells, and synovial fibroblasts. ESTs have been isolated from blood, leukocyte, lung, and placenta libraries.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： FPRL1;ALXR;FMLP R I;FMLP related recepto;FMLP-related recepto;FMLPX;RFP;FPR2_HUMAN;
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