Rabbit Anti-PCGF1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:PCGF1
IR:Immunogen Range:121-220/259
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:84759
Swiss Prot:Q9BSM1
Source:KLH conjugated synthetic peptide derived from human PCGF1:121-220/259
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:PCGF1 is a component of the Polycomb group (PcG) multiprotein BCOR complex, a complex required to maintain the transcriptionally repressive state of some genes, such as BCL6 and the cyclin-dependent kinase inhibitor, CDKN1A. It represses CDKN1A expression by binding to its promoter, and this repression is dependent on the retinoic acid response element (RARE element). PCGF1 als promotes cell cycle progression and also enhances cell proliferation, thus it may have a positive role in tumor cell growth.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Rabbit
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: PCGF1;NSPc1;Nervous system Polyc;Polycomb group RING ;RING finger protein ;RNF68;Polycomb-1;PCGF1_HUMAN;
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