Rabbit Anti-Phospho-TORC2 (Ser171) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Phospho-TORC2 (Ser171)
IR:Immunogen Range:TS(p-S)DS
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:200186
Swiss Prot:Q53ET0
Source:KLH conjugated Synthesised phosphopeptide derived from human CREB regulated transcription coactivator 2 around the phosphorylation site of Ser171:TS(p-S)DS
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2010].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Flow-Cyt(1ug/Test)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: Phospho-TORC2 (Ser17;TORC2 (phospho Ser17;CREB regulated trans;CRTC2;STAT3(Phospho-Tyr705;RP11-422P24.6;TORC-2;CRTC2_HUMAN;
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