Rabbit Anti-phospho-CDK5 (Tyr15) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:phospho-CDK5 (Tyr15)
IR:Immunogen Range:GT(p-Y)GT
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1020
Swiss Prot:Q00535
Source:KLH conjugated synthesised phosphopeptide derived from human CDK5 around the phosphorylation site of Tyr15:GT(p-Y)GT
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:CDK5 (Cyclin Dependent Kinase 5) is serine/threonine kinase involved in synaptic regulation and neuronal development; phosphorylates synaptic protein Pctaire1; regulates acetylcholine receptor expression. CDK5 is a member of the cyclindependent kinase family of serine/threonine kinases. It is present in numerous mammalian tissues including kidney, testes, and ovary. Its activity is detected almost exclusively in brain extracts. Neuronal and muscle cells contain the highest amount of this protein. Similar to other Cdks, monomeric Cdk5 displays no enzymatic activity, but Cdk5 is not activated by cyclins. Instead, the p35 protein, which is expressed solely in the brain, activates Cdk5. Cdk5 interacts with D1 and D3 type G1 cyclins and can phosphorylate histone H1, TAU, MAP2 and NF-H and NF-M. Cdk5 activity is involved in terminal differentiation of neurons and muscle cells.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Mouse
Rat
Chicken
Cow
Horse
Rabbit
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： phospho-CDK5 (Tyr15);Cdk5 (phospho Y15);p-Cdk5(Y15);Cdk 5;Cell division protei;Crk6;PSSALRE;CDK5_HUMAN;
上海沪震实业有限公司是一家集研发、生产和销售于一体的生命科学实验室产品生物科技企业。主营产品：试剂盒，ELISA试剂盒，抗体，重组蛋白，血清，胎牛血清，细胞，原代细胞 细胞培养试剂，常用生化试剂。