Rabbit Anti-Phospho-CaMKII (Thr287) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Phospho-CaMKII (Thr287)
IR:Immunogen Range:QE(p-T)VD
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:815
Swiss Prot:Q9UQM7
Source:KLH conjugated Synthesised phosphopeptide derived from human CaMK2 alpha around the phosphorylation site of Thr287:QE(p-T)VD
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Ca2+/CalmodulinDependent Protein Kinase II (CaM Kinase II) is a multifunctional calcium and calmodulindependent protein kinase that mediates cellular responses to a wide variety of intercellular signals. CaM Kinase II has been shown to regulate diverse cellular functions including synaptic plasticity, neurotransmitter synthesis and release, gene expression, ion channel function, carbohydrate metabolism, cytoskeletal function, and Ca2+homeostasis. Phosphorylation of Thr286 on the kinase produces an autonomously active form of CaM Kinase II. Autophosphorylation of Thr305 inhibits the activity CaM Kinase II. Phosphorylation at this site appears to reduce the association of CaM Kinase II with the PSD and reduce LTP and learning.Size:
50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Rabbit
Sheep
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: Phospho-CaMKII (Thr2;STAT3 (phospho Y705);alpha CaMKII;CaMK II beta subunit;CAMK2A;CAMK2B;CAMK2D;MGC123320;
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