Rabbit Anti-Phospho-Lyn (Tyr507) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Phospho-Lyn (Tyr507)
IR:Immunogen Range:GQ(p-Y)QQ
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:4067
Swiss Prot:P07948
Source:KLH conjugated synthesised phosphopeptide derived from human Lyn around the phosphorylation site of Tyr507:GQ(p-Y)QQ
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Lyn (also known as p53/56 Lyn) is a membrane associated protein tyrosine kinase (PTK) mostly expressed in hemopoietic cells which is important in cellular signaling. It contains an SH2 and SH3 domain and has been found to be cleaved after activation of caspases in apoptosis. A member of the Src family of PTKs, there are two known isoforms for Lyn which plays an indispensable role in the Fc epsilon RI (Fcer1) and the B cell IgM receptor signaling pathway and is essential for Syk activation and Lat phosphorylation after Fcer1 aggregation and can also phosphorylate Tec on multiple residues. Lyn can also be regulated by IL2 and IL3.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Rabbit
Sheep
Guinea Pig
Cat
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: Phospho-Lyn (Tyr507);Lyn (phospho Y507);Lyn (phospho Tyr507);yn (phospho Y508);AA407514;C 2.7.10.2;FLJ26625;LYN_HUMAN;
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