Rabbit Anti-NMDAR3A Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:NMDAR3A
IR:Immunogen Range:531-630/1115
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:116443
Swiss Prot:O60391
Source:KLH conjugated synthetic peptide derived from human NMDAR3A/NR3A:531-630/1115
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:NR3A is a subunit of the N-methyl-D-aspartate (NMDA) receptors, which belong to the superfamily of glutamate-regulated ion channels and function in pathological and physiological processes in the central nervous system. NR3A is a multi-pass membrane protein that is expressed in fetal brain and is mediated by glycine. It may be involved in the development of dendritic spines and in the PPP2CB-NMDAR mediated signaling mechanism. NR3A forms a heteromeric channel composed of a Ω subunit (GRIN1), an e subunit (GRIN2A, GRIN2B, GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B). The NR3A protein is enriched in post-synaptic plasma membrane and post-synaptic densities and requires the presence of GRIN1 to be targeted at the plasma membrane. The NR3A subunit displays greater than 90% sequence homology to the corresponding subunit in rat.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Rabbit
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： NMDAR3A;Chi-1;Glutamate [NMDA] rec;GRIN3A;N-methyl-D-aspartate;N-methyl-D-aspartate;NMDAR3A;NMD3A_HUMAN;
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