Rabbit Anti-Melanoma gp100 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Melanoma gp100
IR:Immunogen Range:21-120/661
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:6490
Swiss Prot:P40967
Source:KLH conjugated synthetic peptide derived from human Melanoma gp100:21-120/661
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Horse
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： Melanoma gp100;95 kDa melanocyte sp;95 kDa melanocyte-sp;D12S53E;gp100;ME20 M/ME20 S;ME20M;PMEL_HUMAN;
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