Rabbit Anti-CYP8B1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:CYP8B1
IR:Immunogen Range:151-250/501
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1582
Swiss Prot:Q9UNU6
Source:KLH conjugated synthetic peptide derived from human CYP8B1:151-250/501
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these two steroids determines the relative amounts of cholic acid and chenodeoxycholic acid both of which are secreted in the bile and affect the solubility of cholesterol. This gene is unique among the cytochrome P450 genes in that it is intronless. [provided by RefSeq, Jul 2008]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Cow
Horse
Sheep
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: CYP8B1;7-alpha-hydroxy-4-ch;CYP12;CYP8B1;CYPVIIIB1;Cytochrome P450 8B1;Cytochrome P450;CP8B1_HUMAN;
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