Rabbit Anti-GSTA1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:GSTA1
IR:Immunogen Range:51-150/222
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:2938
Swiss Prot:P08263
Source:KLH conjugated synthetic peptide derived from human GSTA1/Glutathione S Transferase alpha:51-150/222
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Members of the glutathione S-transferase (GST) family of proteins function in the detoxification of xenobiotics to protect cells against toxicant-induced damage. GSTs are differentially expressed in lung, liver and kidney tissue. Three isoforms, GSTA1-1, GSTA1-4 and GSTM1, localize to the mitochondria in addition to the cytoplasm. In normal and transformed cells, the oncoprotein Myb transcriptionally upregulates GSTM1. This isoform shows high specific activity for aflatoxin B1 epoxide conjugation, suggesting an important role for this interaction in the defense against both chemical and oxidative stress. The C-terminal domain of GSTA1 may form a component of the hydrophobic substrate-binding site, but in contrast appears not to be directly involved in GSH binding and is not absolutely essential for catalytic activity.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Horse
Rabbit
![image.png image.png](/SupplyImg/2023-07-26/6382597799255443996277255.jpg)
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: GSTA1;Glutathione S alkylt;Glutathione S aryltr;GST class alpha 1;GST class alpha memb;GST class alpha;GTH1;GSTA1_HUMAN;
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