Rabbit Anti-FCGRT Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:FCGRT
IR:Immunogen Range:51-150/365
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:2217
Swiss Prot:P55899
Source:KLH conjugated synthetic peptide derived from human FCGRT/FcRn:51-150/365
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:FcRN present in the intestinal epithelium of neonatal mice and rats mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk, thereby helping newborn animals to acquire passive immunity. FcRn (also designated FCGRT, Brambell receptor, FcRn å chain, IgG Gc receptor and neonatal Fc-receptor) is comprised of a heavy chain and ∫-2-Microglobulin. FcRn heavy chain shows approximately 35% amino acid identity to an MHC class I molecule. FcRN localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal catabolism. This protection mechanism is a major constituent for ensuring IgG are the longest lived of all plasma proteins.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(3μg/Test)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Sheep
![image.png image.png](/SupplyImg/2023-07-26/6382598442192187653015706.jpg)
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: FCGRT;IgG receptor FcRn la;Fc fragment of IgG;alpha;FCGRT;FcRn alpha chain;FCRN;FCGRN_HUMAN;
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