Rabbit Anti-phospho-AMPK alpha 1 (Ser496) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:phospho-AMPK alpha 1 (Ser496)
IR:Immunogen Range:SG(p-S)VS
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:5562
Swiss Prot:Q13131
Source:KLH conjugated Synthesised phosphopeptide derived from human AMPK alpha 1 around the phosphorylation site of Ser496:SG(p-S)VS
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: phospho-AMPK alpha 1;phospho-AMPK alpha-1;AMPK alpha-1(phospho;AMPK alpha 1(phospho;AMPK alpha-1;EC 2.7.11.1;AMPK-a;AAPK1_HUMAN;
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