Rabbit Anti-CYP7A1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:CYP7A1
IR:Immunogen Range:321-421/504
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1581
Swiss Prot:P22680
Source:KLH conjugated synthetic peptide derived from human CYP7A1:321-421/504
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis. [provided by RefSeq, Feb 2010].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
Cross Reactive Species:Human
Mouse
Rat
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： CYP7A1;Cholesterol 7 alpha ;Cholesterol 7 alpha ;cholesterol 7 alpha-;Cholesterol 7-alpha-;Cholesterol 7-alpha-;CP7A;CP7A1_HUMAN;
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