Rabbit Anti-Notch 2 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Notch 2
IR:Immunogen Range:1871-1970/2471
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:4853
Swiss Prot:Q04721
Source:KLH conjugated synthetic peptide derived from human Notch 2:1871-1970/2471
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： Notch 2;Neurogenic locus not;activated Notch 2;Notch2;hN2;Notch 2 extracellula;Motch B;NOTC2_HUMAN;
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