Rabbit Anti-OAT-3 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:OAT-3
IR:Immunogen Range:31-110/536
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:83500
Swiss Prot:Q8HY24
Source:KLH conjugated synthetic peptide derived from rat OAT-3:31-110/536
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Human organic anion transporter (OAT) 3 (SLC22A8) is localized to the basolateral membranes of renal tubular epithelial cells and plays a critical role in the excretion of anionic compounds. Recent advances in molecular biology have identified three organic anion transporter families: the organic anion transporter (OAT) family encoded by SLC22A, the organic anion transporting peptide (OATP) family encoded by SLC21A (SLCO), and the multidrug resistance-associated protein (MRP) family encoded by ABCC. These families play critical roles in the transepithelial transport of organic anions in the kidneys as well as in other tissues such as the liver and brain. Among these families, the OAT family plays the central role in renal organic anion transport. Knowledge of these three families at the molecular level, such as substrate selectivity, tissue distribution, and gene localization, is rapidly increasing.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Rabbit
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： OAT-3;Organic anion transp;hOAT3;OAT3;SLC22A8;Solute carrier famil;阴离子转运蛋白-3抗体;S22A8_RAT;
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