Rabbit Anti-DNAJC3 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:DNAJC3
IR:Immunogen Range:351-450/504
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:5611
Swiss Prot:Q13217
Source:KLH conjugated synthetic peptide derived from human p58ipk:351-450/504
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:DNAJC3 may act as an inhibitor of both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2/PKR to catalyze phosphorylation of the EIF2A. It also functions as a Co-chaperone of HSPA8/HSC70 and is involved in the unfolded protein response (UPR) during ER stress. It has been reported that this protein stimulates the ATPase activity of HSPA8/HSC70.DNAJC3 is also involved in ativiral defense - it is activated in response to infection by influenza virus through the dissociation of DNAJB1. DNAJC3 is widely expressed and can be found at high levels in the testis and pancreas (expression in cell lines is variable).
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
![image.png image.png](/SupplyImg/2023-07-27/6382606733780880321325829.jpg)
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: DNAJC3;p58ipk;Protein Kinase Inhib;DnaJ homolog subfami;HP58;P58IPK;PRKRI;DNJC3_HUMAN;
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