Rabbit Anti-phospho-c-Jun (Thr91+Thr93) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:phospho-c-Jun (Thr91+Thr93)
IR:Immunogen Range:TT(p-T)P(p-T)PT
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:3725
Swiss Prot:P05412
Source:KLH conjugated Synthesised phosphopeptide derived from human c-Jun around the phosphorylation site of Thr91/93:TT(p-T)P(p-T)PT
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:C-jun (Oncoprotein C-jun) is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements and appears to be a major downstream target of the SAPK/JNK signaling pathway. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73. Extracellular signals including growth factors, transforming oncoproteins and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. Mutation of Ser63/73 renders c-Jun nonresponsive to mitogenic and stress induced signaling pathways. The MAP kinase homologue, SAPK/JNK, binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73. In addition, the activity of SAPK/JNK is stimulated by the same signals that activate c-Jun.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
Flow-Cyt(1ug/Test)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Rabbit
Sheep
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： phospho-c-Jun (Thr91;c-Jun (phospho T91 +;p-c-Jun(Thr91+Thr93);p-Jun(Thr91+Thr93); Jun oncogene;AP1;Enhancer Binding Pro;JUN_HUMAN;
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