Rabbit Anti-IL-10RA Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:IL-10RA
IR:Immunogen Range:81-180/578
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:3587
Swiss Prot:Q13651
Source:KLH conjugated synthetic peptide derived from human IL-10RA:81-180/578
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: IL-10RA;Interleukin-10 Recep;CD210;CDW210A;CDw210a;CDw210a antigen;HIL10R;I10R1_HUMAN;
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