Rabbit Anti-IL5RA Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:IL5RA
IR:Immunogen Range:11-110/420
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:3568
Swiss Prot:Q01344
Source:KLH conjugated synthetic peptide derived from human IL-5R alpha:11-110/420
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3(IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5(IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Cow
Rabbit
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: IL5RA;Interleukin-5 recept;CD125 antigen;CDw125;HSIL5R3;IL5R;MGC26560;IL5RA_HUMAN;
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