Rabbit Anti-BLNK Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:BLNK
IR:Immunogen Range:301-400/456
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:29760
Swiss Prot:Q8WV28
Source:KLH conjugated synthetic peptide derived from human BLNK:301-400/456
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Flow-Cyt(1μg /test)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Rabbit
![image.png image.png](/SupplyImg/2023-07-28/6382613745413352559832073.jpg)
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: BLNK;B cell adapter conta;B cell adapter conta;B cell linker;BLNK s;Bca;SLP65;BLNK_HUMAN;
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