Rabbit Anti-phospho-MCSF Receptor (Tyr723) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:phospho-MCSF Receptor (Tyr723)
IR:Immunogen Range:DT(p-Y)VE
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1436
Swiss Prot:P07333
Source:KLH conjugated Synthesised phosphopeptide derived from human CSF1R around the phosphorylation site of tyrosine 723:DT(p-Y)VE
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This protein tyrosine kinase transmembrane receptor is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains. CD115 is expressed by cells of the monocytic lineage and by progenitor cells. Mutations in this gene have been associated with a predisposition to myeloid malignancy.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
Flow-Cyt(1ug/Test)
Cross Reactive Species:Human
Mouse
Rat
Dog
Cow
Horse
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: phospho-MCSF Recepto;MCSF Receptor (phosp;p-MCSF Receptor (pho;CSF Receptor;CD115;CD115 antigen;CFMS;CSF1R_HUMAN;
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