Rabbit Anti-ETBR Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:ETBR
IR:Immunogen Range:31-130/442
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1910
Swiss Prot:P24530
Source:KLH conjugated synthetic peptide derived from human EDNRB:31-130/442
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Endothelin receptor type B (ETRB) is a G protein-coupled receptor that activates a phosphatidylinoitol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. A splice variant (SVR), differing in the intracellular C terminal domain, has been described for this receptor. Both WT and the variant bind ET1. However, they exhibit different responses upon binding - suggesting that these two variants are functionally distinct.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Rabbit
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： ETBR;ABCDS;Ednra;Ednrb;Endothelin B recepto;ET-BR;HSCR2;EDNRB_HUMAN;
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