Rabbit Anti-phospho-ATF4 (Ser245) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:phospho-ATF4 (Ser245)
IR:Immunogen Range:NR(p-S)LP
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:468
Swiss Prot:P18848
Source:KLH conjugated Synthesised phosphopeptide derived from human ATF4 around the phosphorylation site of Ser245:NR(p-S)LP
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:ATF4 is a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain (referenced from Entrez gene).
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
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仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： phospho-ATF4 (Ser245;ATF4 (phospho S245);ATF4(Phospho-Ser245);DNA binding protein ;ATF4 protein;CREB2;TAXREB67;ATF4_HUMAN;
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