Rabbit Anti-phospho-RUNX2 (Ser451) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:phospho-RUNX2 (Ser451)
IR:Immunogen Range:TS(p-S)GS
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:860
Swiss Prot:Q13950
Source:KLH conjugated Synthesised phosphopeptide derived from human RUNX2 around the phosphorylation site of Ser451:TS(p-S)GS
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters (By similarity). Inhibits MYST4-dependent transcriptional activation.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
Flow-Cyt(1ug/Test)
Cross Reactive Species:Human
Chicken
Dog
Pig
Cow
Horse
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： phospho-RUNX2 (Ser45;Runx-2;CBF alpha 1;CBFA1;CCD;CCD1;OSF2;OTTHUMP00000016533;
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