Rabbit Anti-HDAC9 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:HDAC9
IR:Immunogen Range:101-200/1011
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:9734
Swiss Prot:Q9UKV0
Source:KLH conjugated synthetic peptide derived from human HDAC9:101-200/1011
Purification:affinity purified by Protein A
Storage:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:HDAC9 (Histone Deacetylase 9) catalyses the deacetylation of lysine residues on the core histones (H2A, H2B, H3 and H4). It belongs to the Class IIa HDAC family, which are key regulators of several developmental and differentiation processes such as cardiac growth. HDAC9 represses MEF2 (myocyte enhancer factor 2)-dependent transcription, playing an important role in cardiac hypertrophy.
The HDAC9 isoform MITR/HDRP lacks active site residues and is therefore catalytically inactive. It represses MEF2-dependent transcription by interacting with HDAC1 and/or HDAC3. MITR/HDRP is thought to play a role in skeletal myogenesis and in heart development. It also protects neurons from apoptosis by inhibiting c-Jun phosphorylation by MAPK10 and by repressing c-Jun transcription through recruitment of HDAC1 to the c-Jun promoter.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Sheep
![image.png image.png](/SupplyImg/2023-07-31/6382639142418047549695713.jpg)
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: HDAC9; HD 7B;HD7; HDAC 7;HDAC 7B;HDAC 9B;HDAC 9FL;HDAC9_HUMAN;
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