Rabbit Anti-FADD Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:FADD
IR:Immunogen Range:51-150/205
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:14082
Swiss Prot:Q13158
Source:KLH conjugated synthetic peptide derived from mouse FADD:51-150/205
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Predicted to enable several functions, including caspase binding activity; death effector domain binding activity; and tumor necrosis factor receptor superfamily binding activity. Involved in several processes, including hematopoietic or lymphoid organ development; negative regulation of activation-induced cell death of T cells; and positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation. Acts upstream of or within extrinsic apoptotic signaling pathway in absence of ligand; motor neuron apoptotic process; and regulation of programmed cell death. Predicted to be located in several cellular components, including cell body; cytosol; and membrane raft. Predicted to be part of CD95 death-inducing signaling complex and ripoptosome. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in leukemia. Orthologous to human FADD (Fas associated via death domain). [provided by Alliance of Genome Resources, Apr 2022]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Mouse
Rat
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: FADD;MORT1;GIG3;IMD90;FAS-associating deat;Mediator of receptor;Fas死亡结构域相关蛋白抗体;FADD_MOUSE;
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