Rabbit Anti-ALOX5AP Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:ALOX5AP
IR:Immunogen Range:65-161/161
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:241
Swiss Prot:P20292
Source:KLH conjugated synthetic peptide derived from human ALOX5AP:65-161/161
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.
Involvement in disease: Genetic variations in ALOX5AP may be a cause of susceptibility to ischemic stroke (ISCHSTR) ; also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Horse
Rabbit
Sheep
![image.png image.png](/SupplyImg/2023-08-01/6382647725616416787059648.jpg)
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: ALOX5AP;5-lipoxygenase activ;5-lipoxygenase activ;ALOX 5AP;ALOX5 AP;Arachidonate 5-lipox;MK 886 binding prote;AL5AP_HUMAN;
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