Rabbit Anti-Laminin 5 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Laminin 5
IR:Immunogen Range:2701-2900/3333
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:3909
Swiss Prot:Q16787
Source:KLH conjugated synthetic peptide derived from human Laminin 5:2701-2900/3333
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminin-5 is thought to be involved in (1) cell adhesion via integrin alpha-3/beta-1 in focal adhesion and integrin alpha-6/beta-4 in hemidesmosomes, (2) signal transduction via tyrosine phosphorylation of pp125-FAK and p80, (3) differentiation of keratinocytes.
Tissue specificity; Skin; respiratory, urinary, and digestive epithelia and in other specialized tissues with prominent secretory or protective functions. Epithelial basement membrane, and epithelial cell tongue that migrates into a wound bed. A differential and focal expression of the subunit alpha-3 is observed in the CNS.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Rabbit
![image.png image.png](/SupplyImg/2023-08-01/6382647927839738496613464.jpg)
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: Laminin 5;E170;Epiligrin 170 kDa su;LAMA3;LAMA3A;Laminin 5 alpha3;LAMNA;LAMA3_HUMAN;
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