Rabbit Anti-Proteasome 19S 10B Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Proteasome 19S 10B
IR:Immunogen Range:301-389/389
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:5706
Swiss Prot:P62333
Source:KLH conjugated synthetic peptide derived from human Proteasome 19S 10B:301-389/389
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The 26S proteasome is a large complex involved in the intracellular degradation of proteins in eukaryotes. Ubiquitination by E3 ubiquitin ligases targets proteins for degradation by this complex. The 26S proteasome plays an important role in the regulation of many biological processes. It is composed of over 30 different subunits and contains at least two copies of each subunit. Assembly of this large complex is ATP-dependent. Due to its size, it is fairly unstable and often disassociates into subcomplexes (including a 20S core and two 19S regulatory complexes). The 26s proteasome p42A (also known as Rpn7 in yeast and S10 in human) is one of at least nine, non-ATPase lid subunits of the 19S regulatory complex. It is important in the proper assembly and stability of the 26S proteasome. The 19S regulatory complex recognizes ubiquitinated proteins, removes the ubiquitin chains and translocates the proteins to the 20S core for degradation.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:50-200)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： Proteasome 19S 10B;26S proteasome;Proteasome 26S subun;Proteasome subunit p;PRS10;PSMC6;SUG2;PRS10_HUMAN;
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