Rabbit Anti-CGAS Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:CGAS
IR:Immunogen Range:251-350/522
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:115004
Swiss Prot:Q8N884
Source:KLH conjugated synthetic peptide derived from human C6orf150:251-350/522
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf150 gene product has been provisionally designated C6orf150 pending further characterization.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Mouse
Rat
Dog
Pig
Horse
![image.png image.png](/SupplyImg/2023-08-01/6382648856693593092862125.jpg)
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: CGAS;Mab-21 Domain Contai;Cyclic GMP-AMP Synth;23-CGAMP Synthas;C6orf150;Chromosome 6 Open Re;MB21D1;CGAS_HUMAN;
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