Rabbit Anti-Etv5 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Etv5
IR:Immunogen Range:301-385/510
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:2119
Swiss Prot:P41161
Source:KLH conjugated synthetic peptide derived from human ERM/Etv5:301-385/510
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Rad and Gem related GTP binding protein (REM) is a member of the RGK subfamily of Ras-like GTPases that also includes Rad, REM2 and Gem/Kir. REM is a phosphorylated protein that is highly expressed in cardiac muscle and moderately expressed in lung, kidney and skeletal muscle. REM associates with several 14-3-3 isoforms as well as with calmodulin in a calcium-dependent manner. REM mediates two distinct signal transduction pathways that regulate both cytoskeletal reorganization and voltage-gated calcium channel activity. REM decreases the current that passes through cardiac voltage-gated L-type Ca channels (Ca(V)). Overexpression of REM may result in the development of cytoplasmic processes, reorganization of the Actin cytoskeleton, reduction in focal adhesion size and an elongated or dendritic-like cell morphology.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Sheep
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: Etv5;ERM;Ets related protein ;ETS translocation va;Ets variant gene 5;Etv5;转录因子Ets差异基因5抗体;ETV5_HUMAN;
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