Rabbit Anti-TCF12 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:TCF12
IR:Immunogen Range:51-150/682
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:6938
Swiss Prot:Q99081
Source:KLH conjugated synthetic peptide derived from human TCF12:51-150/682
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development includes Myo D, myogenin, Myf-5 and Myf-6 (also designated MRF-4 or herculin). Myo D transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. Myo D-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regulatory sequences of many muscle-specific terminal differentiation genes. Both homo- and hetero-oligomers of these proteins are able to distinguish very closely related E box proteins and are believed to play important roles in lineage specific gene expression.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Horse
Rabbit
Zebrafish
Sheep
![image.png image.png](/SupplyImg/2023-08-02/6382656576362561765533263.jpg)
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: TCF12;bHLHb20;Class B basic helix-;DNA binding protein ;HTF4;Tcf12;Transcription factor;HTF4_HUMAN;
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