Rabbit Anti-Syntaxin 13 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Syntaxin 13
IR:Immunogen Range:101-200/274
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:65033
Swiss Prot:G3V7P1
Source:KLH conjugated synthetic peptide derived from rat Syntaxin 13:101-200/274
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Syntaxin 13 is an integral membrane protein that belongs to the t-SNARE family, a group of proteins involved in protein transport. Confocal immunofluoresence and electron microscopy studies have shown that syntaxin 13 is primarily localized to tubular early and recycling endosomes, where it colocalizes with transferrin receptor, and it is also localized in endosomal vacuoles. Syntaxin 13 has been found to be expressed in all tissues, with higher levels of the protein found in brain, lung, spleen, thymus and testes. Immunoprecipitation studies show that syntaxin 13 complexes with beta-SNAP, VAMP2/3, and SNAP25. The binding of this complex to alpha-SNAP and NSF is terminated in the presence of ATP. These results suggest that syntaxin 13 is a SNARE protein which mediates the recycling protein flow through tubulo vesicular recycling endosomes.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Sheep
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: Syntaxin 13;Syx13;Syx-13;CG11278;CT31479;Dm Syx13;ff16;STX12_RAT;
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