Rabbit Anti-Perforin Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Perforin
IR:Immunogen Range:22-100/555
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:5551
Swiss Prot:P14222
Source:KLH conjugated synthetic peptide derived from human Perforin:22-100/555
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008].
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Horse
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: Perforin;Cytolysin;FLH2;HPLH2;MGC65093;P1; SHGC-10760;PERF_HUMAN;
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