Rabbit Anti-ZNF93 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:ZNF93
IR:Immunogen Range:521-620/620
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:81931
Swiss Prot:P35789
Source:KLH conjugated synthetic peptide derived from human ZBT24/ZNF45:521-620/620
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Transcription factor specifically required to repress long interspersed nuclear element 1 (L1) retrotransposons: recognizes and binds L1 sequences and repress their expression by recruiting a repressive complex containing TRIM28/KAP1 (PubMed:25274305). Not able to repress expression of all subtypes of L1 elements. Binds to the 5 end of L1PA4, L1PA5 and L1PA6 subtypes, and some L1PA3 subtypes. Does not bind to L1PA7 or older subtypes nor at the most recently evolved L1PA2 and L1Hs. 50% of L1PA3 elements have lost the ZNF93-binding site, explaining why ZNF93 is not able to repress their expression (PubMed:25274305).
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
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仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： ZNF93;FLJ12488;HPF34;HTF34;TF34;Zinc finger protein ;ZNF505;ZNF93_HUMAN;
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