Rabbit Anti-Keratin 80 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Keratin 80
IR:Immunogen Range:101-200/452
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:144501
Swiss Prot:Q6KB66
Source:KLH conjugated synthetic peptide derived from human Keratin 80:101-200/452
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene's expression profile shows that it encodes a type II epithelial keratin, although structurally the encoded protein is more like a type II hair keratin. This protein is involved in cell differentiation, localizing near desmosomal plaques in earlier stages of differentiation but then dispersing throughout the cytoplasm in terminally differentiating cells. The type II keratins are clustered in a region of chromosome 12q13. Two transcript variants encoding two different fully functional isoforms have been found for this gene.[provided by RefSeq, Oct 2010]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: Keratin 80;CK 80;Cytokeratin 80;K80;KB20;Krt80;type II cytoskeletal;K2C80_HUMAN;
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