Rabbit Anti-NDFIP2 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:NDFIP2
IR:Immunogen Range:261-336/336
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:54602
Swiss Prot:Q9NV92
Source:KLH conjugated synthetic peptide derived from human NDFIP2:261-336/336
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:NDFIP2 is a 336 amino acid protein that localizes to the membrane of both the endosome and the golgi apparatus. Expressed in kidney, heart, brain, lung, liver, placenta and skeletal muscle, Ndfip2 interacts with NEDD4 and NEDD4-L and is thought to be involved in endocytosis and in the NFⅹB and MAPK signaling pathways. Additionally, Ndfip2 may function as an adaptor protein that may recruit NEDD4 ubiquitin-protein ligases to protein trafficking machinery in the golgi. Ndfip2 is activated by T cells and may be ubiquitinated by NEDD4 or NEDD4-L, an event that does not affect Ndfip2 function. The gene encoding Ndfip2 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Rabbit
Sheep
![image.png image.png](/SupplyImg/2023-08-04/6382673885516193785426768.jpg)
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: NDFIP2;Ndfip2;NEDD4 family interac;NEDD4 family-interac;Putative MAPK ;PM04/PM05/PM06/PM07;Putative NF-kappa-B-;NFIP2_HUMAN;
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