Rabbit Anti-Collagen alpha-1(I) chain Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Collagen alpha-1(I) chain
IR:Immunogen Range:1051-1218
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1277
Swiss Prot:P02452
Source:KLH conjugated synthetic peptide derived from human Collagen alpha-1(I) chain:1051-1218
Purification:affinity purified by Protein A
Storage:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008].
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
![image.png image.png](/SupplyImg/2023-08-04/6382673993311259309137296.jpg)
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: Collagen alpha-1(I) ;Collagen type I;Alpha 1 type I colla;COL1A1;Collagen type I alph;Osteogenesis Imperfe;1型胶原蛋白;CO1A1_HUMAN;
上海沪震实业有限公司是一家集研发、生产和销售于一体的生命科学实验室产品生物科技企业。主营产品:试剂盒,ELISA试剂盒,抗体,重组蛋白,血清,胎牛血清,细胞,原代细胞 细胞培养试剂,常用生化试剂。