Mouse Anti-CD68 Monoclonal Antibody
DATASHEET
Host:Mouse
Target Protein:CD68
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:968
Swiss Prot:P34810
Source:Recombinant human CD68 1-100/354aa:
Purification:affinity purified by Protein G
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008].
Size:50ul
Concentration:1mg/ml
Applications:IHC-P(1:100-300)
Cross Reactive Species:Human
Mouse
Rat
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: CD68;CD68 antigen;CD68 molecule;DKFZp686M18236;GP110;Macrophage antigen C;LAMP4;CD68_MOUSE;
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