Mouse Anti-CA9 Monoclonal Antibody
DATASHEET
Host:Mouse
Target Protein:CA9
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:768
Swiss Prot:Q16790
Source:Recombinant human Carbonic Anhydrase IX (full length):
Purification:affinity purified by Protein G
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. [provided by RefSeq, Jul 2008]
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:500-1000)
Cross Reactive Species:Human
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仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: CA9;CA IX;CA-IX;Carbonate dehydratas;G250;P54/58N;pMW1;CAH9_HUMAN;
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