Rabbit Anti-Phospho-Stat2 (Tyr690) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Phospho-Stat2 (Tyr690)
IR:Immunogen Range:RK(p-Y)LK
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:6773
Swiss Prot:P52630
Source:KLH conjugated Synthesised phosphopeptide derived from human Stat2 around the phosphorylation site of Tyr690:RK(p-Y)LK
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Horse
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: Phospho-Stat2 (Tyr69;Stat2 (phospho-Tyr69;Stat2 (phospho Tyr69;P113;signal transducer an;STAT113;p113;STAT2_HUMAN;
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